Search results for " Mimetic"

Types of Mimetics for the Design of Intelligent Technologies

2019

Mimetic design means using a source in the natural or artificial worlds as an inspiration for technological solutions. It is based around the abstraction of the relevant operating principles in a source domain. This means that one must be able to identify the correct level of analysis and extract the relevant patterns. How this should be done is based on the type of source. From a mimetic perspective, if the design goal is intelligent technology, an obvious source of inspiration is human information processing, which we have called cognitive mimetics. This article offers some conceptual clarification on the nature of cognitive mimetics by contrasting it with biomimetics in the context of in…

Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer

2016

Recent studies have correlated physical activity with a better prognosis in cachectic patients, although the underlying mechanisms are not yet understood. In order to identify the pathways involved in the physical activity-mediated rescue of skeletal muscle mass and function, we investigated the effects of voluntary exercise on cachexia in colon carcinoma (C26)-bearing mice. Voluntary exercise prevented loss of muscle mass and function, ultimately increasing survival of C26-bearing mice. We found that the autophagic flux is overloaded in skeletal muscle of both colon carcinoma murine models and patients, but not in running C26-bearing mice, thus suggesting that exercise may release the auto…

PPARδ Modulation by GW501516: An Unsuccessful Exercise Mimetic.

2017

Cognitive mimetics : Main ideas

2018

The modern era of emerging intelligent technologies necessitates the development of technologyspecific design methods. Artificial intelligence (AI), robots, and autonomous systems are expected to replace humans in many intelligent information-processing tasks. To develop such systems, however, designers need to understand what happens in the minds of the people completing such tasks today. Designers also need methods to develop intelligent technological solutions. In the present paper, we discuss cognitive mimetics as a possible tool for designers of intelligent technologies. Like biomimetics, cognitive mimetics is an analogy-based method; however, instead of looking for structural and mate…

FIctional Artworks. Literary Ékphrasis and the Invention of Images

2016

The volume is devoted to images in painting, photography and cinema invented by literature. At the same time it intends to question, through this perspective, the relationship between text and image, between verbal and visual in modern and contemporary literature. The authors investigate the mutual boundaries between literature and arts from the point of view of aesthetics, visual culture and literary theory, trying to build a map of the notional ékphrasis, a description which constitutes the work of art while telling it.

An ontology for cognitive mimetics

2018

AI and autonomous systems are intended to replace people in several jobs. People have worked in these jobs being able to execute the required information processing. This implies that new technical artefacts must be able to perform equitably effective information processing. Thus, it makes sense to develop the analysis of human information processing in designing intelligent systems. This approach has been termed cognitive mimetics. This paper studies how it would be practical to gain knowledge about human information processing and organize this knowledge using ontologies.

Questions in Cognitive Mimetics

2021

Human thinking advances through questions and answers. Any field of human endeavor is permeated by the presence of questions, answers and presuppositions. Questions have a kind of universality, whereby one can place the question marks on anything, including questions themselves. The process of asking the right questions about the right things and in the right way are key for the explication of an approach. Recently, we have begun thinking about an approach to the design of intelligent technology: Cognitive mimetics. In brief, the idea is to take inspiration of empirical human thinking in specific contexts to develop AI solutions. The purpose of this article is to question this approach from…

Malonato complexes of oxidovanadium(IV): Synthesis, structural characterization and exploration of their insulin mimetic properties

2011

Abstract Several bis-malonatooxidovanadium(IV) complexes of the general type [M2(H2O)n][VO(mal)2(H2O)] (where M = Li(1), Na(2), K(3), Cs(4) and NH4(5); n = 3.5, 1, 3, 1 and 1, respectively) were isolated in good yield and high purity. These complexes were fully characterized by various physicochemical techniques (elemental analysis, UV–Vis, IR, EPR, CV, etc.) complexes 1, 2 and 3 were structurally characterized by single crystal X-ray diffraction technique. In vivo antidiabetic properties of bis-malonato complexes 1, 2, 3 and 5 have been studied using Streptozotocin induced diabetic rats. Significant lowering of blood sugar level has been noticed. At the same time these complexes were found…

Conceptual basis of cognitive mimetics for information engineering

2021

Abstract Intelligent information processing is topical in modern technology design and development. The fundamental idea was developed by Turing as he made the first conceptual models of information-processing computers. Though it has practically never been noticed, Turing’s work was a model of how to mimic human intelligent information processes and generate technologies, which can carry out intelligent tasks. The design method can be called cognitive mimetics as it imitates human information processes to design technologies and their applications. One can use cognitive mimetics even in solving techno-ethical problems. This is why we think that cognitive mimetics are vital as a method to g…

Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone

2021

Osteoporotic vertebral fractures often necessitate fusion surgery, with high rates of implant failure. We present a novel bioactive composite of calcium phosphate cement (CPC) and the collagen I mimetic P-15 for pedicle screw augmentation in osteoporotic bone. Methods involved expression analysis of osteogenesis-related genes during osteoblastic differentiation by RT-PCR and immunostaining of osteopontin and Ca2+ deposits. Untreated and decalcified sheep vertebrae were utilized for linear pullout testing of pedicle screws. Bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry (DEXA). Expression of ALPI II (p &lt